$1,200/person$200/night
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Cruises from Port of San Diego
Upcoming sailings and the ships and cruise lines that call at Port of San Diego, San Diego, United States.
37 ship calls, since Jul 20267 cruise lines
Upcoming sailings from Port of San Diego
7 Night Ensenada, Cabo & La Paz Cruise
Royal Caribbean • Serenade of the Seas
Oct 25, 2026 · 7 nights
Mexico
$509/person$73/night
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$1,014/person$169/night
View Deal$1,264/person$181/night
View Deal7 Night Ensenada, Cabo & Mazatlan Cruise
Royal Caribbean • Serenade of the Seas
Nov 1, 2026 · 7 nights
Mexico
$512/person$73/night
View Deal$634/person$211/night
View Deal$777/person$194/night
View Deal$2,477/person$177/night
View Deal7 Night Ensenada, Cabo & Mazatlan Cruise
Royal Caribbean • Serenade of the Seas
Nov 8, 2026 · 7 nights
Mexico
$912/person$130/night
View Deal$758/person$190/night
View Deal$961/person$320/night
View Deal
$799/person$114/night
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Ship calls, since Jul 2026
Who sails from Port of San Diego
Ships
- Disney MagicDisney Cruise Line9 calls since Jul 2026
- Disney WonderDisney Cruise Line5 calls since Jul 2026
- Serenade of the SeasRoyal Caribbean International5 calls since Jul 2026
- Brilliant LadyVirgin Voyages4 calls since Jul 2026
- National Geographic EnduranceLindblad Expeditions4 calls since Jul 2026
- ZaandamHolland America Line2 calls since Jul 2026
Planning
About cruising from Port of San Diego
Port of San Diego is a port of call in San Diego, United States. It is part of the California cruise region.
Port of San Diego appears on many itineraries as a stop. Ships give passengers time to explore the town before sailing on.
Booking tips
- Compare itineraries and fares across the lines that sail here.
- Check shore excursion options before you sail.
- Sailings vary by season. Book early for the busiest months.
Where to stay
Hotels near Port of San Diego
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Hotels & Accommodations Near Port of San Diego
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Shore excursions and activities
Find tours, excursions, and activities near Port of San Diego
Browse activitiesFAQ
Questions about cruising from Port of San Diego
What cruise lines sail from Port of San Diego?
We tracked 7 cruise lines at Port of San Diego since Jul 2026. The busiest are Disney Cruise Line, Holland America Line, Royal Caribbean International.
Is Port of San Diego a turnaround port?
Port of San Diego is mainly a port of call that ships visit during an itinerary.
How many cruise ships call at Port of San Diego?
Our AIS tracking recorded 37 ship calls since Jul 2026, about 2.3 a week.
When is the best time to cruise from here?
It depends on the itinerary and the weather you want. The seasonality tab shows which months are busiest at Port of San Diego.